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Your skin is your largest organ responsible for protecting your body from a variety of outside forces, but it is also the most visible part of you, and is susceptible to environmental, physical and hormonal conditions which can make your skin tone appear blotchy and uneven.

You may want to use non-toxic, natural products on your skin to keep it healthy and vibrant, but there are lots of choices out there how can you be sure which one is best for your skin?

Revitol Skin Brightener Cream uses safe, plant-based ingredients to help reduce the appearance of freckles, liver-spots, and uneven pigmentation areas while keeping your skin soft and supple with natural emollients, moisturizers and skin-nourishing vitamins. It's a great way to lighten and brighten the appearance of those trouble spots safely with nature's finest ingredients.

Contains no mercury or other harmful ingrdedients

The active ingredients in Revitol Skin Brightener Cream lighten the appearance of skin and promote a healthy, balanced-looking complexion. We use natural ingredients such as:

  • Arbutin: Extracted from the bearberry plant, and also found in wheat and pear skins, Arbutin helps reduce the appearance of dark areas.
  • Lumiskin: Also known as Diacetyl Boldine, inhibits Tryosinase to help lighten the appearance of the skin and promote more evenlooking skin tone.
  • Shea Butter: Derived from the nut of the Karite Nut tree (mangifolia), Shea butter has been used by African women for centuries for both cooking and for its healing properties in skin care. It contains natural sun protectants and emollients, and is used in many moisturizers, soaps and skin creams to firm and tighten skin.
  • Evening Primrose Oil: Used as a food and natural medicine throughout history, Primrose is effective in skin care to help alleviate dry skin.
  • Allantoin: A botanical extract of the comfrey plant, Allantoin is a natural-identical, non-toxic moisturizer that promotes the health of the outer dermal layer.
  • Grapefruit Seed Extract: Used as a preservative, this extract is a natural antioxidant.
  • Vitamins A, C and E: Because it has a fundamental role in the control of normal skin cell activity, Vitamin A is very important to healthy skin, and adding the antioxidant vitamins C and E gives this important skin nutrient extra support (for a complete list of ingredients, view our ingredients page).

Read what these health-conscious customers are saying about Revitol Skin Brightener Cream:

"I tried to brighten the appearance of my skin before, but the product I used gave me a horrible rash. I didn't think I'd ever try again. I found out that Revitol Skin Brightener has Arbutin and lots of other great ingredients, so I figured this time I'd be safe, and I was. Plus my skin is lighter and so pretty and healthy-looking! I never looked this good before!
H.M., New York, NY

"I wanted a fairer looking complexion, but I try to take good care of myself and just use what's natural. When I saw that Revitol Skin Brightener has Arbutin, which is a natural ingredient, I figured it was time to go for it. I'm so glad I did! I got just what I wanted, with absolutely beautiful skin!"
B.V., Little Rock, AR

"I always wanted lighter, healthier-looking skin, but I was afraid to do anything about it because I heard that a lot of products have ingredients that can make your skin worse than before. When I saw that Revitol Skin Brightener uses natural ingredients, I decided to take a chance. Now, after just a few weeks, my skin appears lighter, and it looks wonderful!"
T.J., Los Angeles, CA

*Results will vary

90 Day Money Back Guarantee.

We take great pride in the superior quality of our products and want you to be pleased with your purchase. We believe in offering the very best value, quality and selection to our customers. You may return any unused and unopened item purchased from us for any reason within Ninety (90) days of your purchase. Customer Care

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April 5, 2015. Hyperpigmentation - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/Hyperpigmentation)

Learn about Deformities, Dystrophies, and Discoloration of the Nails symptoms, diagnosis and treatment in the Merck Manual. HCP and Vet versions too!


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March 29, 2015. Disorders of Pigmentation: Slideshow - Medscape Drugs... (http://reference.medscape.com/features/slideshow/pi gmentation)

Viral and Bacterial Infections of the Skin - Free ebook download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text file (.txt) or view presentation slides online.


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March 23, 2015. Skin Disorders Archives - DermaTalk (http://www.dermatalk.com/blogs/category/skin-disord ers/)

Diabetic Foot Care & Monitoring. As a resident training in the Salt Lake City VA Hospital, I was exposed to the full gamut of diabetic foot wounds, infections...


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April 2, 2015. What Are the Causes of Toenail Discoloration? | LIVESTRONG.COM (http://www.livestrong.com/article/248958-what-are-t he-causes-of-toenail-discoloration/)

Nail diseases are distinct from diseases of the skin. Although nails are a skin appendage, they have their own signs and symptoms which may relate to other medical...



March 24, 2015. chemical_nfpa_codes.xls - Arizona State University | A top... (http://www.asu.edu/uagc/EHS/documents/chemical_nfpa _codes.xls)

clinical cases and pearls benjamin barankin, md, frcpc anil kurian, md


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April 4, 2015. Deformities, Dystrophies, and Discoloration of the Nails... (http://www.merckmanuals.com/home/skin_disorders/nai l_disorders/deformities_dystrophies_and_discolorati on_of_the_nails.html)

Neutrophilic eccrine hidradenitis (NEH) was initially described in acute myelogenous leukemia (AML) patients undergoing chemotherapy. [1] Neutrophilic...


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March 28, 2015. Hyperpigmentation: Pigmentation Disorders: Merck Manual... (http://www.merckmanuals.com/professional/dermatolog ic_disorders/pigmentation_disorders/hyperpigmentati on.html)

Treatment for recalcitrant plantar warts can be time-consuming and the options for treatment have differing levels of success. Accordingly, the authors share pearls...


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April 11, 2015. Patient Care Services Stanford, CA 94305 Bleomycin (blee... (http://healthlibrary.stanford.edu/patient/bleomycin.pdf)

Bleomycin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.



April 9, 2015. Management of keloids and hypertrophic scars: current and... (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639020 /)

September 14, 2010 Skin Changes and Cancer Treatments: Tips for Healthy Skin and Hair Carolyn Goh, MD & Jenny Kim, MD, PhD


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April 1, 2015. List of skin disorders - Psychology Wiki (http://psychology.wikia.com/wiki/List_of_skin_disor ders)

HYPERPIGMENTATION. What is hyperpigmentation? Hyperpigmentation is a darkening of the skin. This can occur as an overall darkening of the skin, or it can be...


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March 26, 2015. How To Treat Recalcitrant Plantar Warts | Podiatry Today (http://www.podiatrytoday.com/how-treat-recalcitrant -plantar-warts)

Reasons for Drug Reaction Skin Rashes. The reasons why skin rashes may occur with using certain drugs can be discussed under drug allergies or non-allergic drug...


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April 3, 2015. Neutrophilic Eccrine Hidradenitis - Diseases & Conditions... (http://emedicine.medscape.com/article/1070937-overv iew)

Clinical Presentation: Drug-Induced Pigmentation. Adverse cutaneous reactions to medications are a common reason for consultations with dermatologists.



March 30, 2015. Skin Reactions - Managing Side Effects - Chemocare (http://chemocare.com/chemotherapy/side-effects/skin -reactions.aspx)

Learn about Hyperpigmentation symptoms, diagnosis and treatment in the Merck Manual. See Home and Vet versions too!


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March 22, 2015. Human skin pigmentation: melanocytes modulate skin color... (http://www.fasebj.org/content/21/4/976.full)

Doxil official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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April 10, 2015. Bleomycin - FDA prescribing information, side effects and uses (http://www.drugs.com/pro/bleomycin.html)

Surgical aspects for the prevention and treatment of keloids and hypertrophic scars. Surgical approaches for the prevention and treatment of hypertrophic...


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April 8, 2015. Skin Changes and Cancer Treatments: Tips for Healthy Skin... (http://www.simmsmanncenter.ucla.edu/index.php/cente r_events/skin-changes-and-cancer-treatments-tips-fo r-healthy-skin-and-hair/)

Idiopathic Pulmonary Fibrosis Clinical Trials. Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and...



March 27, 2015. Viral and Bacterial Infections of the Skin - Scribd (https://www.scribd.com/doc/21209680/Viral-and-Bacte rial-Infections-of-the-Skin)

Dermatology is a book containing the following 34 chapters: Acne Vulgaris, Anatomy, Bacterial Infections, Cardiovascular Medicine, Dermatitis, Dry Skin, Endocrinology...


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April 7, 2015. What Causes Idiopathic Pulmonary Fibrosis? - NHLBI, NIH (http://www.nhlbi.nih.gov/health/health-topics/topic s/ipf/causes)

History: A 54-year-old, lightly pigmented woman of African, Indian, and Caucasian descent was noted to have a bluish discoloration of her sclera on routine...


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April 6, 2015. DJO | Digital Journal of Ophthalmology - Harvard University (http://www.djo.harvard.edu/print.php?url=/physician s/gr/1399&print=1)

In dermatology, hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin. Contents 1 Causes 2 Treatment 3 See also 4 References 5...


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March 21, 2015. Derm book - Upload, Share, and Discover Content on SlideShare (http://www.slideshare.net/ARHGrandRounds/derm-book)

What Does Numbness and Tingling Mean? Numbness means decreased or absent sensation in the skin; the medical terms are hypoesthesia and anesthesia.



March 31, 2015. Nail disease - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/Nail_disease)

Disorders of pigmentation present as skin that is discolored, blotchy, or darker or lighter than normal. They occur when the body produces too little...


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March 25, 2015. Drug Reaction Skin Rash and Medication Causing Skin... (http://www.healthhype.com/drug-reaction-skin-rash-a nd-medication-causing-skin-eruptions.html)

z y x w v u t s r q p o n m l k j i h g f e d c b a agarase 37288-57-6 agarose 9012-36-6 age antibodies & age related antibodies agfa developer (g-101c) agfa...


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April 26, 2015. Dermatology - Family Practice Notebook (http://www.fpnotebook.com/Derm/index.htm)

Skin Tumors, Vascular Lesions, Face and Neck. Vascular lesions of the head and neck encompass a wide range of different lesions.


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April 27, 2015. Patient Education Resources for Medical Professionals... (http://vivacare.com/)

Dermatology is a book containing the following 34 chapters: Acne Vulgaris, Anatomy, Bacterial Infections, Cardiovascular Medicine, Dermatitis, Dry Skin, Endocrinology...


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April 28, 2015. Treatment of Nongenital Cutaneous Warts - American Family... (http://www.aafp.org/afp/2011/0801/p288.html)

HYPERPIGMENTATION. What is hyperpigmentation? Hyperpigmentation is a darkening of the skin. This can occur as an overall darkening of the skin, or it can be...



April 29, 2015. Drug-induced skin pigmentation. DermNet NZ (http://www.dermnetnz.org/reactions/drug-pigmentatio n.html)

Clinical Presentation: Drug-Induced Pigmentation. Adverse cutaneous reactions to medications are a common reason for consultations with dermatologists.


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April 30, 2015. Common skin disorders of the penis. - National Center for... (http://www.ncbi.nlm.nih.gov/pubmed/12175386)

Drug-induced skin pigmentation. Authoritative facts about the skin from DermNet New Zealand.


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May 1, 2015. BEP chemotherapy - Cancer Information - Macmillan Cancer... (http://www.nhs.uk/ipgmedia/national/macmillan%20can cer%20support/assets/bepmcs5pages.pdf)

1. BJU Int. 2002 Sep;90(5):498-506. Common skin disorders of the penis. Buechner SA(1). Author information: (1)Department of Dermatology, University of...


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May 2, 2015. Deformities, Dystrophies, and Discoloration of the Nails... (http://www.merckmanuals.com/home/skin-disorders/nai l-disorders/deformities-dystrophies-and-discolorati on-of-the-nails)

In dermatology, hyperpigmentation is the darkening of an area of skin or nails caused by increased melanin. Contents 1 Causes 2 Treatment 3 See also 4 References 5...



May 3, 2015. DJO | Digital Journal of Ophthalmology - Harvard University (http://www.djo.harvard.edu/print.php?url=/physician s/gr/1399&print=1)

Learn about Deformities, Dystrophies, and Discoloration of the Nails symptoms, diagnosis and treatment in the Merck Manual. HCP and Vet versions too!



May 19, 2015. Recent Developments in Nanoparticulate Drug Delivery... (http://www.academia.edu/1115537/Recent_Developments _in_Nanoparticulate_Drug_Delivery_Systems)

Treatment for recalcitrant plantar warts can be time-consuming and the options for treatment have differing levels of success. Accordingly, the authors share pearls...



May 20, 2015. Drug-Induced Pigmentation Clinical Presentation (http://emedicine.medscape.com/article/1069686-clini cal)

The mechanism(s) of neutrophilic eccrine hidradenitis is unknown, although neutrophilic eccrine hidradenitis pathologic changes observed with intradermal...



May 21, 2015. Nail Discoloration - Family Practice Notebook (http://www.fpnotebook.com/Derm/Nails/NlDsclrtn.htm)

Drug-induced skin pigmentation. Authoritative facts about the skin from DermNet New Zealand.



May 22, 2015. DJO | Digital Journal of Ophthalmology - Harvard University (http://www.djo.harvard.edu/print.php?url=/physician s/gr/1399&print=1)

Page 1 of 7 - BEP chemotherapy - Macmillan 2014 BEP chemotherapy BEP is a chemotherapy treatment used to treat testicular cancer and a rare type of ovarian cancer.



May 23, 2015. Blenoxane (Bleomycin Sulfate Injection) Drug Information... (http://www.rxlist.com/blenoxane-drug/indications-do sage.htm)

Learn about Deformities, Dystrophies, and Discoloration of the Nails symptoms, diagnosis and treatment in the Merck Manual. HCP and Vet versions too!


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August 10, 2015. Drug Eruptions - Medscape (http://misc.medscape.com/pi/android/medscapeapp/htm l/A1049474-business.html)

Ifosfamide official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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August 11, 2015. Homo sapiens diseases - Cutaneous apparatus and... (http://www.ufrgs.br/imunovet/molecular_immunology/p athohomotissueskin.html)

What Does Numbness and Tingling Mean? Numbness means decreased or absent sensation in the skin; the medical terms are hypoesthesia and anesthesia.


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August 12, 2015. Lists of RxNorm INgredients, Tradenames, and Package (http://discern.uits.iu.edu:8421/simple-list-of-RxNo rm-IN-BN-BPCK.html)

The moment you discover bumps or lumps under skin, first thing that comes on your mind is: what the hell is this, could it be cancer? Well, it is common to experience...



August 13, 2015. HIV InSite - Treatment of HIV-Associated Kaposi Sarcoma (http://hivinsite.ucsf.edu/InSite?page=kb-00&doc =kb-06-02-04)

Vascular lesions of the head and neck encompass a wide range of different lesions. Historically, these lesions have been poorly understood, and their...


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August 14, 2015. Skin Lesion Facts - TheFreeDictionary Medical Dictionary (http://medical-dictionary.thefreedictionary.com/Ski n+Lesions)

This page includes the following topics and synonyms: Nail Discoloration, Leukonychia, Melanonychia, Chromonychia, White Nails, Yellow Nails, Black Nails, Green Nails...


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August 15, 2015. Wart Removal | Laser Center of Maryland (http://www.lasercentermd.com/conditions/warts/)

NAIL CHANGES. What are nail changes? There are several types of nail changes which may occur in patients receiving chemotherapy. The most common of these skin...


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August 16, 2015. Bleomycin (APP Pharmaceuticals, LLC): FDA Package Insert... (http://druginserts.com/lib/rx/meds/bleomycin-1/page /2/)

Learn about Deformities, Dystrophies, and Discoloration of the Nails symptoms, diagnosis and treatment in the MSD Manual. HCP and Vet versions too!



August 17, 2015. Bleomycin for Injection, USP - National Institutes of Health (http://dailymed.nlm.nih.gov/dailymed/archives/fdaDr ugInfo.cfm?archiveid=15883)

Page 2: APP Pharmaceuticals, LLC: Bleomycin for Injection should be considered a palliative treatment. It has been shown to be useful in the management of the...


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August 18, 2015. Chemotherapy - Bleomycin - Lymphoma Info (http://www.lymphomainfo.net/therapy/drugs/bleomycin.html)

Bleomycin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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September 13, 2015. Hyperpigmentation - Dermatologic Disorders - Merck Manuals... (http://www.merckmanuals.com/professional/dermatolog ic-disorders/pigmentation-disorders/hyperpigmentati on)

Practice Essentials. Drug eruptions can mimic a wide range of dermatoses. The morphologies are myriad and include morbilliform, urticarial, papulosquamous, pustular...


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September 14, 2015. Skin Tumors, Vascular Lesions, Face and Neck: Overview... (http://emedicine.medscape.com/article/846692-overvi ew)

Diseases of skin (see also physiology of skin) Pathogenetic processes: with regard to the stratum corneum and stratum granulosum; parakeratosis: process of...


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September 15, 2015. Bellevue Laser and Cosmetic Center | What would you like... (http://bellevuelasercenter.com/skin-conditions/what -would-you-like-to-treat)

Vascular lesions of the head and neck encompass a wide range of different lesions. Historically, these lesions have been poorly understood, and their...



September 16, 2015. Stomatitis | definition of stomatitis by Medical dictionary (http://medical-dictionary.thefreedictionary.com/sto matitis)

Numerous treatments for nongenital cutaneous warts are available, although no single therapy has been established as completely curative. Watchful waiting is an...


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September 17, 2015. Bleomycin: Package Insert and Label Information (Page 2 of 2) (http://druginserts.com/lib/rx/meds/bleomycin-1/page /2/)

Skin Lesions Definition A skin lesion is a superficial growth or patch of the skin that does not resemble the area surrounding it. Description Skin lesions can be...


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September 18, 2015. Bleomycin - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/Bleomycin)

Bleomycin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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September 28, 2015. Skin discoloration - Symptom Checker - check medical... (http://symptoms.rightdiagnosis.com/cosymptoms/skin- discoloration.htm)

Skin discoloration - bluish. Toggle: English / Spanish. Definition. Cyanosis is a bluish color to the skin or mucus membranes that is usually due to a lack of oxygen...


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September 29, 2015. Hyperpigmentation - Definition of Hyperpigmentation (http://lymphoma.about.com/od/glossary/g/Hyperpigmen tation.htm)

Healthy-looking, even-toned skin is a goal for most women, but even with the best intentions, skin can still fall victim to uneven pigmentation and discoloration.


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September 30, 2015. Skin Problems & Treatments: Overview & Facts - WebMD (http://www.webmd.com/skin-problems-and-treatments/g uide/skin-problems-treatments-overview-facts)

How To Get Rid Of Skin Discoloration 1. How To Get Rid Of Skin Discoloration 2. What Are The Causes? Post Inflammatory Hyperpigmentation (Acne Scars...



October 1, 2015. Medications that Cause Skin Pigmentation - DermaTalk (http://www.dermatalk.com/blogs/skin-disorders/medic ations-that-can-cause-skin-pigmentation/)

List of 25 causes of Skin discoloration, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.


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October 2, 2015. Skin discoloration? - Lymphoma.com - Lymphoma Support and... (http://forums.lymphoma.com/showthread.php?t=27624)

Definition: Hyperpigmentation is a darkening or discoloration of the skin, nails and mucous membranes. It is a common side effect of radiation therapy and chemotherapy.


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October 3, 2015. Bleomycin: Current Status and New Developments (http://www.researchgate.net/publication/46830747_Bl eomycin_Current_Status_and_New_Developments)

Skin discoloration? Hodgkin's Peer Support and News... Yup, that'll be the bleomycin. It seems to affect some people more than others.


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October 4, 2015. Skin discoloration? [Archive] - Lymphoma.com - Lymphoma... (http://forums.lymphoma.com/archive/index.php/t-2762 4.html)

Irregular or patchy discoloration of the skin can be caused by: Changes in melanin, a substance produced in the skin cells that gives skin its color



October 5, 2015. Bleomycin induced flagellate erythema: Revisiting a unique... (http://www.cancerjournal.net/article.asp?issn=0973- 1482;year=2013;volume=9;issue=3;spage=500;epage=503 ;aulast=Biswas)

Discoloration can occur in areas... which may occur in patients receiving chemotherapy. The most common of these skin reactions... or worsening skin rash.


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October 6, 2015. Bleomycin and Swelling - Reviews - Treato (http://treato.com/Bleomycin,Swelling/?a=s)

Bleomycin induced flagellate dermatitis is a rare and unique adverse effect. With the declining use of bleomycin, this complication is becoming increasingly...


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October 7, 2015. Skin Discoloration Causes - HowStuffWorks (http://health.howstuffworks.com/skin-care/problems/ medical/skin-discoloration1.htm)

Bleomycin is irritating and can cause pain or a burning feeling along the... Discoloration of your skin in areas that have been treated with radiation.


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October 8, 2015. Causes of Skin discoloration - RightDiagnosis.com (http://www.rightdiagnosis.com/symptoms/skin_discolo ration/causes.htm)

Want to learn about Bleomycin and Swelling? Find out on Treato what other patients are saying.



October 9, 2015. Bleomycin therapy for cystic hygroma - ScienceDirect (http://www.sciencedirect.com/science/article/pii/00 22346895904859)

Skin discoloration causes range from sun exposure to infection. Learn more about skin discoloration causes at HowStuffWorks.


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October 10, 2015. Minocycline-induced hyperpigmentation: comparison of 3 Q... (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674755 /)

Drug-induced skin pigmentation. Authoritative facts about the skin from DermNet New Zealand.


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October 11, 2015. Bleomycin therapy for cystic hygroma (http://www.researchgate.net/publication/14676545_Bl eomycin_therapy_for_cystic_hygroma)

Minocycline-induced hyperpigmentation is associated with long-term use of this drug. Any patient receiving more than 100 grams of minocycline can develop...


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October 12, 2015. Discolored Skin Patches: 38 Causes, Photos & Treatments (http://www.healthline.com/health/discolored-skin-pa tches)

Bleomycin therapy for cystic hygroma on... Minor transient side effects (fever, vomiting, cellulitis, skin discoloration)... Bleomycin aqueous solution was...



October 13, 2015. Flagellate erythema. DermNet NZ (http://www.dermnetnz.org/reactions/flagellate.html)

Discover causes of discolored skin patches including sunburn, eczema, contact dermatitis, and others. Learn about evaluation and treatments.


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October 14, 2015. Bleomycin induced flagellate pigmentation Lalit Kumar... (http://www.ijdvl.com/article.asp?issn=0378-6323;yea r=2002;volume=68;issue=3;spage=158;epage=159;aulast =Gupta)

Flagellate erythema is an uncommon patterned rash... causes vasodilation with local bleomycin accumulation in the skin causing a subsequent fixed drug eruption.


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December 5, 2015. Bleomycin - Cancer Information - Macmillan Cancer Support (http://www.macmillan.org.uk/Cancerinformation/Cance rtreatment/Treatmenttypes/Chemotherapy/Individualdr ugs/Bleomycin.aspx)

BLEOMYCIN SULFATE USP : Faulding : Antineoplastic Action And Clinical Pharmacology: Experiments with isolated DNA have shown that bleomycin binds to the DNA molecule...


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December 6, 2015. Skin toxicity of chemotherapy drugs. DermNet NZ (http://www.dermnetnz.org/reactions/chemotherapy-tox icity.html)

Vanquish dark spots and skin discoloration, replacing uneven and ill-textured skin with smooth, wrinkle-free skin that leaves you looking flawless and ageless.


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December 7, 2015. Bleomycin: A worthy alternative - National Center for... (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111124 /)

Bleomycin: Skin side effects and intralesional use for skin conditions; Other websites: Books about skin diseases: See the DermNet NZ bookstore.



December 8, 2015. Bleomycin induced flagellate pigmentation. - ResearchGate (http://www.researchgate.net/publication/6181823_Ble omycin_induced_flagellate_pigmentation)

Drug-induced skin disorders... pigmentation caused by bleomycin. Skin dyschromia... jaundice and this drug-induced skin discoloration.


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December 9, 2015. Skin discoloration - RightDiagnosis.com (http://www.rightdiagnosis.com/sym/skin_discoloratio n.htm)

Minor transient side effects (fever, vomiting, cellulitis, skin discoloration)... Bleomycin aqueous solution was injected... Bleomycin therapy for cystic hygroma.


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December 10, 2015. Pruritic Discoloration Following ABVD Therapy | Cancer Network (http://www.cancernetwork.com/image-iq/pruritic-disc oloration-following-abvd-therapy)

More Skin discoloration animations & videos Medications or substances causing Skin discoloration: The following drugs, medications, substances or toxins are some of...


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December 11, 2015. Bleomycin - Wikipedia, the free encyclopedia (https://en.wikipedia.org/wiki/Bleomycin)

Flagellate erythema is an uncommon patterned rash... causes vasodilation with local bleomycin accumulation in the skin causing a subsequent fixed drug eruption.



December 12, 2015. Bleomycin: skin side effects and... - DermNet NZ (http://www.dermnetnz.org/treatments/bleomycin.html)

Bleomycin is a medication used to... by injection into a muscle or under the skin. [1]... and Raynaud's phenomenon (discoloration of fingers and toes...


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December 13, 2015. Post bleomycin skin discolouration - Scientific Figure on... (http://www.researchgate.net/figure/51452026_fig5_Po st-bleomycin-skin-discolouration)

Bleomycin: skin side effects and intralesional use for skin conditions. Authoritative facts about the skin from DermNet New Zealand.


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December 14, 2015. Bleomycin skin discoloration - Hydroxycut - Weight Loss... (http://hydroxycut.herbalous.com/bleomycin-skin-disc oloration.html)

Bleomycin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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January 5, 2016. Pathophysiology of irradiated skin and breast - ScienceDirect (http://www.sciencedirect.com/science/article/pii/03 6030169400423I)

Quinacrine Hydrochloride Drug Information from Drugs.com. Includes Quinacrine Hydrochloride side effects, interactions and indications.


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January 6, 2016. Nail disease - Wikipedia, the free encyclopedia (https://en.wikipedia.org/wiki/Nail_disease)

Raynaud's phenomenon (RAY-noz), in medicine, is a vasospastic disorder causing discoloration of the fingers, toes, and occasionally other extremities, named for...


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January 7, 2016. Category - Medicaljournals.se (http://www.medicaljournals.se/acta/index.php?option =com_content&view=article&id=22&Itemid= 7)

Nail diseases are distinct from diseases of the skin. Although nails are a skin appendage, they have their own signs and symptoms which may relate to other medical...



January 8, 2016. Causes of Numbness and Tingling (Paresthesia) in Fingertips (http://www.hxbenefit.com/causes-of-numbness-and-tin gling-paresthesia-in-fingertips.html)

Articles by category (Starting issue 4, volume 86, 2006.) Atopy Drug development and adverse reactions Editorials and general subjects Epidemiology and socioeconomics


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January 9, 2016. Quinacrine Hydrochloride Drug Information, Professional (http://www.drugs.com/mmx/quinacrine-hydrochloride.h tml)

What Does Numbness and Tingling Mean? Numbness means decreased or absent sensation in the skin; the medical terms are hypoesthesia and anesthesia.


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Quinacrine Hydrochloride Drug Information from Drugs.com. Includes Quinacrine Hydrochloride side effects, interactions and indications.


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January 11, 2016. Pathophysiology of irradiated skin and breast - ScienceDirect (http://www.sciencedirect.com/science/article/pii/03 6030169400423I)

Diseases of skin (see also physiology of skin) Pathogenetic processes: with regard to the stratum corneum and stratum granulosum; parakeratosis: process of...



January 12, 2016. Nail disease - Wikipedia, the free encyclopedia (https://en.wikipedia.org/wiki/Nail_disease)

The evolution, time course, and dose response of gross and histologic changes associated with the acute and late changes of the skin are noted and a composite p


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LIVESTRONG.COM; Fashion, Style and Personal Care; Grooming; Grooming Hands and Feet; What Are the Causes of Toenail Discoloration?


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January 14, 2016. BLEOMYCIN FOR INJECTION, USP - DailyMed (http://dailymed.nlm.nih.gov/dailymed/archives/fdaDr ugInfo.cfm?archiveid=2232)

HYPERPIGMENTATION. What is hyperpigmentation? Hyperpigmentation is a darkening of the skin. This can occur as an overall darkening of the skin, or it can be...


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February 3, 2016. Skin Cancer and Benign Tumor Image & Information Gallery (http://www.warts.org/skin-cancer-and-benign-tumor-i mage-&-information-gallery.htm)

September 14, 2010 Skin Changes and Cancer Treatments: Tips for Healthy Skin and Hair Carolyn Goh, MD & Jenny Kim, MD, PhD


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February 4, 2016. Skin changes with chemotherapy - Canadian Cancer Society (http://www.cancer.ca/en/cancer-information/diagnosi s-and-treatment/chemotherapy-and-other-drug-therapi es/chemotherapy/side-effects-of-chemotherapy/skin-c hanges-with-chemotherapy/?region=on)

Nail diseases are distinct from diseases of the skin. Although nails are a skin appendage, they have their own signs and symptoms which may relate to other medical...


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February 5, 2016. BEP chemotherapy - Cancer Information - Macmillan Cancer... (http://www.macmillan.org.uk/Cancerinformation/Cance rtreatment/Treatmenttypes/Chemotherapy/Combinationr egimen/BEP.aspx)

Minor skin changes or skin irritation can occur during and for some time after chemotherapy. Not all chemotherapy drugs cause skin changes, but it is important to be...



February 6, 2016. Hypertrophic Scarring and Keloids: Pathomechanisms and... (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978 /)

Find out more about BEP (bleomycin, etoposide, cisplatin), a combination chemotherapy treatment for testicular cancer and a rare type of ovarian cancer


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February 7, 2016. ABVD Chemotherapy - Lymphoma Info (http://www.lymphomainfo.net/therapy/chemotherapy/ab vd.html)

Skin Lesions Definition A skin lesion is a superficial growth or patch of the skin that does not resemble the area surrounding it. Description Skin lesions can be...


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February 8, 2016. DailyMed - BLEOMYCIN- bleomycin sulfate injection, powder... (http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?s etid=2ef2901b-e3ee-47ba-81d9-48c6668fd19b)

HYPERPIGMENTATION. What is hyperpigmentation? Hyperpigmentation is a darkening of the skin. This can occur as an overall darkening of the skin, or it can be...


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February 9, 2016. Bleomycin | definition of bleomycin by Medical dictionary (http://medical-dictionary.thefreedictionary.com/ble omycin)

It is recommended that Bleomycin for Injection USP be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic...



February 10, 2016. BLEOMYCIN - INJECTION (Blenoxane) side effects, medical... (http://www.medicinenet.com/bleomycin-injection/arti cle.htm)

Brand Name: Blenoxane. Bleomycin is a chemotherapy drug that is administered for the treatment of several types of cancer, including squamous cell carcinomas...


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March 2, 2016. How To Remove Your Warts and Skin Tags in 3 days (http://www.rrnursingschool.biz/skin-tags.html)

Mitoxantrone is for intravenous (IV) use only. If mitoxantrone accidentally leaks into surrounding tissue, the skin or muscle may become severely damaged.


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March 3, 2016. Hyperpigmentation - Wikipedia, the free encyclopedia (https://en.wikipedia.org/wiki/Hyperpigmentation)

Dr. Ian H. Beiser's Podiatry Page ***** Dr. Beiser is a podiatrist serving patients in the Washington, DC, area


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March 4, 2016. Nail Problems - Podantics Podiatry Adelaide (http://www.podantics.com.au/nail-problems.html)

Skin Tumors, Vascular Lesions, Face and Neck. Author: Jeremy D Prager, MD; Chief Editor: Arlen D Meyers, MD, MBA more...



March 5, 2016. DailyMed - PHENYTOIN SODIUM- phenytoin sodium injection (http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?set id=035a8d4e-2063-4240-83cb-d7eebcabe301)

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March 6, 2016. Pharmacology - Rx-wiki (http://rx-wiki.org/index.php?title=Pharmacology)

WARNING: CARDIOVASCULAR RISK ASSOCIATED WITH RAPID INFUSION. The rate of intravenous Phenytoin Sodium Injection administration should not exceed 50 mg per...


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March 7, 2016. Mitoxantrone: Indications, Side Effects, Warnings - Drugs.com (http://www.drugs.com/cdi/mitoxantrone.html)

What Does Numbness and Tingling Mean? Numbness means decreased or absent sensation in the skin; the medical terms are hypoesthesia and anesthesia.


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March 8, 2016. Common Foot Problems - Dr. Ian H. Beiser's Podiatry Page Home (http://www.beiserpodiatry.com/commonfootproblems.ht m)

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March 9, 2016. How To Remove Your Warts and Skin Tags in 3 days (http://www.rrnursingschool.biz/skin-tags.html)

Dr. Ian H. Beiser's Podiatry Page ***** Dr. Beiser is a podiatrist serving patients in the Washington, DC, area


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March 10, 2016. Hyperpigmentation - Wikipedia, the free encyclopedia (https://en.wikipedia.org/wiki/Hyperpigmentation)

Skin Tumors, Vascular Lesions, Face and Neck. Author: Jeremy D Prager, MD; Chief Editor: Arlen D Meyers, MD, MBA more...


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March 11, 2016. Nail Problems - Podantics Podiatry Adelaide (http://www.podantics.com.au/nail-problems.html)

My Moles Warts and Skin Tags Removal Review. The author presents a well detailed summery of the major headings. As a professional in this field, I must say that the...


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March 12, 2016. Melasma/Hyperpigmentation - Advanced Skin Wisdom (http://www.advancedskinwisdom.com/melasma.htm)

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March 13, 2016. Percutaneous Sclerotherapy for Facial Venous Malformations... (http://www.ajnr.org/content/31/5/955.full)

Epidemiology. The occurrence of keloids and hypertrophic scars has equal sex distribution and the highest incidence in the second to third decade (17,18).


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April 3, 2016. Bleomycin-induced Scleroderma - ResearchGate (http://www.researchgate.net/profile/Rohini_Handa/pu blication/8096962_Bleomycin-induced_scleroderma/lin ks/00b7d53443f558e046000000.pdf?origin=publication_ detail)

Bleomycin induced flagellate erythema: Revisiting a unique complication... Bleomycin induced flagellate erythema: Revisiting... bleomycin hydrolase in human skin.


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April 4, 2016. RxMed: Pharmaceutical Information - BLEOMYCIN SULFATE USP (http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1. monographs/CPS-%20Monographs/CPS-%20(General%20Mono graphs-%20B)/BLEOMYCIN%20SULFATE%20USP.html)

Find a comprehensive guide to possible side effects when taking Blenoxane (Bleomycin Sulfate Injection) for Professionals, Patients, and Caregivers.


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April 5, 2016. Blenoxane (Bleomycin Sulfate Injection) Drug... - RxList (http://www.rxlist.com/blenoxane-drug/indications-do sage.htm)

Learn about the potential side effects of bleomycin. Includes common and rare side effects information for consumers and healthcare professionals.



April 6, 2016. Lymphangitis as a complication of intralesional bleomycin... (http://www.jaad.org/article/S0190-9622(98)70097-0/p df)

Bleomycin-induced Scleroderma Shefali K Sharma*... discoloration of fingers on exposure to cold... idiopathic scleroderma.2 Also bleomycin-induced skin


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April 7, 2016. Bleomycin - DailyMed (https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXs l.cfm?setid=905e0984-2ce3-481c-b1a0-0ef0a616479a)

Bleomycin: skin side effects and intralesional use for skin conditions. Authoritative facts about the skin from DermNet New Zealand.


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April 8, 2016. Bleomycin for Injection, USP - DailyMed (https://dailymed.nlm.nih.gov/dailymed/archives/fdaD rugInfo.cfm?archiveid=15883)

Intralesional Bleomycin in Lymphangioma: An Effective and Safe Non-Operative Modality of Treatment... and skin discoloration in 10 patients. Conclusion:


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April 9, 2016. Deformities, Dystrophies, and Discoloration of the Nails... (http://www.merckmanuals.com/home/skin-disorders/nai l-disorders/deformities,-dystrophies,-and-discolora tion-of-the-nails)

Bleomycin is irritating and can cause pain or a burning feeling along the... Discoloration of your skin in areas that have been treated with radiation.



April 10, 2016. Skin color - patchy: MedlinePlus Medical Encyclopedia (https://www.nlm.nih.gov/medlineplus/ency/article/00 3224.htm)

Discoloration can occur in areas of pressure... Skin reactions may include skin blistering and erosions. This syndrome is frequently drug induced.


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April 11, 2016. Bleomycin: MedlinePlus Drug Information (https://www.nlm.nih.gov/medlineplus/druginfo/meds/a 682125.html)

Bleomycin is a medication used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer, and cervical cancer among...


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April 12, 2016. Post bleomycin skin discolouration - Scientific Figure on... (https://www.researchgate.net/figure/51452026_fig5_P ost-bleomycin-skin-discolouration)

Bleomycin injection is used alone or in combination with other medications to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue...


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May 3, 2016. Blenoxane (Bleomycin Sulfate Injection) Drug... - RxList (http://www.rxlist.com/blenoxane-drug/indications-do sage.htm)

Bleomycin therapy for cystic hygroma on ResearchGate, the professional network for scientists.


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May 4, 2016. Bleomycin - Wikipedia, the free encyclopedia (https://en.m.wikipedia.org/wiki/Blenoxane)

... skin discoloration caused by minocycline... Causes of blue discoloration of the skin... chlorpromazine, phenacetin, minocycline), doxorubicin, bleomycin...


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May 5, 2016. Bleomycin therapy for cystic hygroma. (http://www.ncbi.nlm.nih.gov/pubmed/8523225)

Intralesional bleomycin injection was used as sclerosant therapy for sixteen patients with cystic hygroma. An excellent (complete clinical resolution) response



May 6, 2016. Lymphangitis as a complication of intralesional bleomycin... (http://www.jaad.org/article/S0190-9622(98)70097-0/p df)

Bleomycin therapy for cystic hygroma... Minor transient side effects (fever, vomiting, cellulitis, skin discoloration)... The results suggest that bleomycin...


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May 7, 2016. Bleomycin Side Effects in Detail - Drugs.com (http://www.drugs.com/sfx/bleomycin-side-effects.htm l)

Answer. C. The adverse event was caused by bleomycin. Discussion. Bleomycin has also been associated with diffuse and patchy skin darkening, as well as pigmentation...


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May 8, 2016. BLEOMYCIN - INJECTION (Blenoxane) side effects, medical... (http://www.medicinenet.com/bleomycin-injection/arti cle.htm)

Learn about the potential side effects of bleomycin. Includes common and rare side effects information for consumers and healthcare professionals.


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October 7, 2016. Bleomycin - Blenoxane | Diablo Valley Oncology - DVOHMG (https://dvohmg.com/patients/cancer-pharmacy-san-fra ncisco/medication-library/blenoxane-bleomycin/)

Percutaneous Sclerotherapy for Facial Venous Malformations: Subjective Clinical and... using bleomycin for... skin discoloration over the...


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October 8, 2016. Bleomycin therapy for cystic hygroma | DeepDyve (https://www.deepdyve.com/lp/elsevier/bleomycin-ther apy-for-cystic-hygroma-wsOgMf8IG7)

PubMed journal article Bleomycin therapy for cystic hygrom was found in Unbound MEDLINE. Download PubMed App to iPhone, iPad, Android smartphone and tablet.


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October 9, 2016. Hyperpigmentation Definition and Side Effect of Chemotherapy (https://www.verywell.com/hyperpigmentation-2252088)

Intralesional bleomycin in lymphangioma: an effective and safe... evaluated the efficacy of intralesional Bleomycin as a... skin discoloration in 10...



October 10, 2016. Bleomycin induced flagellate pigmentation - researchgate.net (https://www.researchgate.net/publication/6181823_Bl eomycin_induced_flagellate_pigmentation)

Bleomycin is an antibiotic chemotherapy medication used to treat head and neck... skin changes, nail discoloration and rash are additional potential side effects of...


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October 11, 2016. Intralesional Bleomycin in Lymphangioma: An Effective and... (http://europepmc.org/articles/PMC3461790)

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October 12, 2016. Lymphangitis as a complication of intralesional bleomycin... (http://www.jaad.org/article/S0190-9622(98)70097-0/p df)

Bleomycin is irritating and can cause pain or a burning feeling along the... Discoloration of your skin in areas that have been treated with radiation.


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October 13, 2016. BLEOMYCIN - INJECTION (Blenoxane) side effects, medical... (http://www.medicinenet.com/bleomycin-injection/arti cle.htm)

Bleomycin therapy for cystic hygroma... Minor transient side effects (fever, vomiting, cellulitis, skin discoloration)... The results suggest that bleomycin...



October 14, 2016. Flagellate erythema | DermNet New Zealand (http://www.dermnetnz.org/topics/flagellate-erythema /)

DESCRIPTION. Bleomycin for injection, USP, is a sterile mixture of cytotoxic glycopeptide antibiotics isolated from a strain of Streptomyces verticillus.


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October 15, 2016. Bleomycin Side Effects in Detail - Drugs.com (https://www.drugs.com/sfx/bleomycin-side-effects.ht ml)

Bleomycin: Skin side effects and intralesional use for skin conditions; Other websites: Books about skin diseases: See the DermNet NZ bookstore. Make a donation.


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October 16, 2016. Skin discoloration from Bleomycin injection : AskDocs (https://www.reddit.com/r/AskDocs/comments/520f1a/sk in_discoloration_from_bleomycin_injection/)

Learn about the potential side effects of bleomycin. Includes common and rare side effects information for consumers and healthcare professionals.


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October 17, 2016. Bleomycin skin discoloration - Revitol Skin Brightner... (http://skinbrightener.herbalous.com/bleomycin-skin- discoloration.html)

Bleomycin induced flagellate pigmentation Lalit Kumar Gupta, RK Tanwar, Ashok Kumar Khare, Suresh Kumar Jain Department of Skin, STD & Leprology and Radiotherapy...



October 18, 2016. Bleomycin - FDA prescribing information, side effects and uses (https://www.drugs.com/pro/bleomycin.html)

Procarbazine molecule Brand Name: Blenoxane Bleomycin is a chemotherapy drug that is administered for the treatment of several types of cancer, including squamous...


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October 19, 2016. Bleomycin and the skin | DermNet New Zealand (http://www.dermnetnz.org/topics/bleomycin/)

Bleomycin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.


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November 9, 2016. Drug: Bleomycin Oncology - Intravenous Dilution Data (http://globalrph.com/bleomycin.htm)

Percutaneous Sclerotherapy for Facial Venous Malformations: Subjective Clinical and... using bleomycin for... skin discoloration over the...


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November 10, 2016. Original Article Bleomycin: A worthy alternative? (https://www.researchgate.net/profile/Paras_Kothari/ publication/51452026_Bleomycin_A_worthy_alternative /links/0deec538b6aa89c8d4000000.pdf?origin=publicat ion_detail)

Drug: Bleomycin: The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment.


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November 11, 2016. Bleomycin-induced Scleroderma (https://www.researchgate.net/profile/Rohini_Handa/p ublication/8096962_Bleomycin-induced_scleroderma/li nks/00b7d53443f558e046000000.pdf?origin=publication _list)

Discoloration can occur in areas of pressure... Bleomycin, cyclophosphamide... Skin reactions may include skin blistering and erosions.



November 12, 2016. DailyMed - BLEOMYCIN- bleomycin sulfate injection, powder... (https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?se tid=B5806C40-12CE-48E3-8ABD-9F8997EF4428)

Answer. C. The adverse event was caused by bleomycin. Discussion. Bleomycin has also been associated with diffuse and patchy skin darkening, as well as pigmentation...


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November 13, 2016. Lymphangitis as a complication of intralesional bleomycin... (http://www.jaad.org/article/S0190-9622(98)70097-0/p df)

Bleomycin is irritating and can cause pain or a burning feeling along the... Discoloration of your skin in areas that have been treated with radiation.


bleomycin skin discoloration picture 6


November 14, 2016. Bleomycin therapy for cystic hygroma. (https://www.ncbi.nlm.nih.gov/pubmed/8523225)

Learn about the potential side effects of bleomycin. Includes common and rare side effects information for consumers and healthcare professionals.


bleomycin skin discoloration picture 7


November 15, 2016. BLEOMYCIN - INJECTION (Blenoxane) side effects, medical... (http://www.medicinenet.com/bleomycin-injection/arti cle.htm)

WARNING. It is recommended that Bleomycin for Injection be administered under the supervision of a qualified physician experienced in the use of cancer...



November 16, 2016. Drug-induced skin pigmentation | DermNet New Zealand (http://www.dermnetnz.org/topics/drug-induced-skin-p igmentation/)

Bleomycin induced flagellate pigmentation Lalit Kumar Gupta, RK Tanwar, Ashok Kumar Khare, Suresh Kumar Jain Department of Skin, STD & Leprology and Radiotherapy...


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